Abstract: AIM: The aim of this study was to assess the demography of Polymyositis in Iran. Methods: In the past 20 years, we had seen 124 patients in Rheumatology Research Center. All patients were classified by the American College of Rheumatology classification criteria. Ninety five items were checked for every patient. All patients were followed regularly and the data were updated at each visit. Results: Seventy one patients were female. The female to ...
Abstract: Aim: The aim of this study was to assess the demography of polymyositis in Iranian children. Methods: 47 children classified by the ACR Criteria as having polymyositis were studied. 95 items were checked for every patient. They were followed regularly and the data were updated at each visit. Results: Thirty patients were female (64%). The acute presentation of the disease was seen in 10%. The manifestations at the onset of ...
Abstract: Aim: The aim of this study was to determine the clinical and the laboratory features of scleroderma in Iranian patients. Methods: This is a prospective study done on 350 patients from 1975 to 1995. The diagnosis of scleroderma was based on the clinical and the skin biopsy. One hundred clinical and laboratory data were completed for every patients . Results: The mean age was 29.7 years with a standard deviation (SD) of ...
Abstract: Scleroderma may occur in childhood with different characteristics. The present study shows the picture of scleroderma in Iranian children and compares the characteristics in children and adults. Methods: 56 scleroderma patients under 16 were compared with 217 adult scleroderma seen since 1975. Data were compared with Chi square test. Results: Girls were 44 (79%) and boys 12. The initial presentation was: Raynaud's phenomenon 68%, skin edema 27%, limb skin sclerosis 66%, ...
Abstract: Aim: The aim of this study was to assess the demography of SLE in Iran. Methods: In the past 20 years, each patient referred to the Lupus Unit had a computerized form with 266 items. All patients were followed regularly and the data were updated at each visit. Results: We have seen 1310 SLE patients with the following characteristics: The mean age was 24 years, females 89.5%, males 10.5 %, fever 58%, ...
Abstract: In systemic lupus eryThematosus (SLE) various antibodies are produced against cells including platelets and result in thrombocytopenia. !n the literature, the incidence of thrombocytopenia varied from 7% to 52%, in seven series of SLE patients with a mean cumulative percentage of 14.5% (1-5 ). SLE patients referred to the Lupus Unit of the Rheumatology Research Center. Tehran University for Medical Sciences. (Shariati Hospital) during the period of 1975 to 1977 ...
Abstract: Behcet's disease (BD) is not ran in Iran. The annual incidence is around 345 patients for a population of 60 millions. The male/female ratio is 1. 13. The mean age at the onset of the disease is 26.2+9.7 years (CI at 95%=0 .4). The prevalence of clinical signs were as follow: Mucous membrane lesions 96%+0.7 (oral aphthosis 95.7%, genital aphthosis 64%); skin lesions 74%±I.5 (pseudofolliculitis 66%, erythema nodosum 23%): ocular ...
Abstract: Considering that the majority of BD patients are from APLAR (Asia and Pacific League of Associations for Rheumatology) countries any diagnosis criteria for BD must have an adequate accuracy in these countries. The APLAR subcommittee for Behcet's Disease has set a prospective study to assess the accuracy of the existing diagnosis criteria. China, Iran, Japan, and Korea, the major countries with BD are participating to this study. The data from ...
Abstract: Introduction: Behcet's disease (BD) is a multisystem disorder with potential ability to influence pregnancy outcome. Changes in the BD may also occur during pregnancy. This study was designed to find the effect of pregnancy on BD and the outcome of pregnancy. Materials & Methods: We analyzed 59 pregnancies in 54 women with BD. The disease activity during pregnancy and in the 6 month period both before pregnancy and after delivery were ...
Abstract: Introduction: Ocular lesions are the major cause of morbidity in Behcet's Disease. If not treated, they usually progress toward severe loss of vision or blindness. Cytotoxic drugs are the main therapeutic arsenal used for this condition. Materials & Methods: in an open, non randomized control study. Pulse Cyclophosphamida (PCP), low dose pulse cyclophosphamide (LDP), oral cyclophosphamide (OCP). weakly methotrexate (MTX), chlorambucil (CHL), and cyclosporine A (CYA) were used in a standard ...